Overview
Recce’s New Classes of Synthetic Anti-infectives are designed to address the urgent global health threat posed by antibiotic resistant superbugs and emerging viral pathogens. Recce Pharmaceuticals have developed two primary drug candidates: RECCE® 327 for bacterial infections and RECCE® 529 for viral infections. RECCE® 529 is a new synthetic polymer formulation with indication against viruses. All RECCE® compounds are 100% water soluble at all pH levels in their liquid form. Recce Pharmaceuticals continues to strengthen and expand their product pipeline in order to find a treatment for ‘difficult to treat’ bacterial and viral infections.
RECCE® 327 - Bacterial Infections
There is a historic lack of innovation in the antibiotic drug development field to address this growing need for effective antibiotics. RECCE® 327 is one of the first new classes of antibiotics in over 30 years with a universal mechanism of action that allow its compounds to continuously kill bacteria and multi-drug resistant superbugs.
What Bacteria has RECCE® 327 demonstrated capability against?
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Clostridium difficile
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Helicobacter pylori
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Streptococcus pyogenes
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Neisseria gonorrhoeae
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Escherichia coli
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Enterococcus faecium
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Staphylococcus aureus
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Klebsiella pneumoniae
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Acinetobacter baumannii
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Pseudomonas aeruginosa
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Enterococcus species
ESKAPE Pathogens
Dubbed ESKAPE for their propensity of ‘escaping’ the biocidal action of antibiotics, the acronym stands for six different commonly found multi-drug resistant pathogens: Enterococcus faecium (E. faecium), Staphylococcus aureus (S. aureus), Klebsiella pneumoniae (K. pneumoniae), Acinetobacter baumannii (A. baumannii), Pseudomonas aeruginosa (P. aeruginosa) and Enterobacter species.
An independent study was conducted by a contract research organisation to assess the in vitro efficacy of R327 against all ESKAPE pathogen bacterial strains. The results demonstrated R327 to be 99.9% effective against the full suite of ESKAPE pathogens, within hours of exposure.
RECCE® 529 – Viral Infections
The Company is undertaking initial studies of RECCE® 529 to indicate any potential therapeutic effect against SARS-CoV-2 (the virus causing the disease ‘Coronavirus’ or ‘COVID-19’).
Designed with a Purpose
RECCE® 327's Unique and Multi-layered Mechanism of Action
R327 Mechanism of Action 'unlike that of any antibiotic seen before' with multiple mechanisms identified. R327 rapidly and irreversibly bactericidal against Gram-negative Escherichia coli (E. coli) bacteria, in both active and stationary phase cells - outperforming best in class commercial antibiotics.
Tackling Superbugs
See how R327 tackles superbugs and treats blood infections and sepsis derived from E. coli and S. aureus bacteria – including their superbug forms.